Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.55 |
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963557 | 0.90 | CNR2 (0.56) | CNR2CNR1MEN1KMT2ARAB9A | |
| SCHEMBL3965017 | 0.87 | CNR2 (0.49) | CNR2CNR1MEN1KMT2ARAB9A | |
| SCHEMBL3965021 | 0.85 | CNR2 (0.50) | CNR2CNR1MEN1KMT2ARAB9A | |
| SCHEMBL1464539 | 0.82 | NPC1 (0.61) | CNR2CNR1MEN1KMT2ARAB9A | |
| SCHEMBL1465761 | 0.82 | CNR2 (0.78) | CNR2CNR1MEN1KMT2ARAB9A | |
| SCHEMBL1463670 | 0.76 | NPC1 (0.56) | CNR2CNR1MEN1KMT2ARAB9A | |
| SCHEMBL1463526 | 0.76 | CNR2 (0.75) | CNR2CNR1MEN1KMT2ARAB9A | |
| SCHEMBL3966620 | 0.75 | CNR2 (0.52) | CNR2CNR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1465703 | 0.75 | CNR2 (0.80) | CNR2CNR1MEN1KMT2ARAB9A | |
| SCHEMBL4011827 | 0.74 | CNR2 (0.52) | CNR2CNR1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |