Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965021 | 0.91 | CNR2 (0.50) | CNR2CNR1RAB9AMEN1KMT2A | |
| SCHEMBL3963555 | 0.87 | CNR2 (0.55) | CNR2CNR1RAB9AMEN1KMT2A | |
| SCHEMBL3963557 | 0.85 | CNR2 (0.56) | CNR2CNR1RAB9AMEN1KMT2A | |
| SCHEMBL3963536 | 0.84 | CNR2 (0.44) | CNR2CNR1MEN1KMT2AMAPK1 | |
| SCHEMBL3959609 | 0.80 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL1465761 | 0.77 | CNR2 (0.78) | CNR2CNR1RAB9AMEN1KMT2A | |
| SCHEMBL1464539 | 0.77 | NPC1 (0.61) | CNR2CNR1RAB9AMEN1KMT2A | |
| SCHEMBL1464232 | 0.73 | GAA (0.62) | CNR2CNR1RAB9AMEN1KMT2A | |
| SCHEMBL4017166 | 0.72 | CNR2 (0.46) | CNR2CNR1RAB9AMEN1KMT2A | |
| SCHEMBL1465703 | 0.72 | CNR2 (0.80) | CNR2CNR1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |