Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.81 |
| ▸ | PGR | P06401 | 2/20 | 0.73 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.73 |
| ▸ | AR | P10275 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968522 | 0.91 | NR3C1 (0.84) | NR3C1PGRNR3C2AR | |
| SCHEMBL3968164 | 0.91 | NR3C1 (0.85) | NR3C1PGRNR3C2AR | |
| SCHEMBL3969455 | 0.90 | NR3C1 (0.83) | NR3C1PGRNR3C2AR | |
| SCHEMBL3962750 | 0.90 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL3962862 | 0.90 | NR3C1 (0.82) | NR3C1PGRNR3C2AR | |
| SCHEMBL3963043 | 0.90 | NR3C1 (0.82) | NR3C1PGRNR3C2AR | |
| SCHEMBL3969506 | 0.90 | NR3C1 (0.82) | NR3C1PGRNR3C2AR | |
| SCHEMBL7190281 | 0.90 | NR3C1 (0.82) | NR3C1PGRNR3C2AR | |
| SCHEMBL3965658 | 0.89 | NR3C1 (0.85) | NR3C1PGRNR3C2AR | |
| SCHEMBL3963160 | 0.89 | NR3C1 (0.85) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363876-B1 | GLUCOCORTICOID RECEPTOR MODULATORS | KAROBIO AB (SE) | 2009-07-29 | — | — | EP | disclosed |