Gamma-Tocopherol

Gamma-Tocopherol

SCHEMBL39640

Cc1c(O)cc2c(c1C)OC(C)(CCCC(C)CCCC(C)CCCC(C)C)CC2

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 13/20 0.91
PDPK1 O15530 3/20 0.91
PHLPP1 O60346 3/20 0.91
ILK Q13418 3/20 0.91
LMNA P02545 3/20 0.72
MAPT P10636 2/20 0.65
MEN1 O00255 1/20 0.65
GSTP1 P09211 1/20 0.65
TTPA P49638 1/20 0.65
KMT2A Q03164 1/20 0.65
USP2 O75604 1/20 0.65
THRB P10828 1/20 0.65
CYP2C9 P11712 1/20 0.65
CYP2C19 P33261 1/20 0.65
NR1I2 O75469 2/20 0.62
ALOX5 P09917 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gamma-Tocopherol SCHEMBL14695405 1.00 AKT1 (0.91) AKT1PDPK1PHLPP1ILKLMNA
Gamma-Tocopherol SCHEMBL120346 1.00 AKT1 (0.91) AKT1PDPK1PHLPP1ILKLMNA
Gamma-Tocopherol SCHEMBL17874900 1.00 AKT1 (0.91) AKT1PDPK1PHLPP1ILKLMNA
Gamma-Tocopherol SCHEMBL14580952 1.00 AKT1 (0.91) AKT1PDPK1PHLPP1ILKLMNA
Gamma-Tocopherol SCHEMBL16430717 1.00 AKT1 (0.91) AKT1PDPK1PHLPP1ILKLMNA
Gamma-Tocopherol SCHEMBL29373100 1.00 AKT1 (0.91) AKT1PDPK1PHLPP1ILKLMNA
Gamma-Tocopherol SCHEMBL8408124 1.00 AKT1 (0.91) AKT1PDPK1PHLPP1ILKLMNA
SCHEMBL15441242 1.00 AKT1 (0.91) AKT1PDPK1PHLPP1ILKLMNA
Gamma-Tocopherol SCHEMBL29620131 1.00 AKT1 (0.91) AKT1PDPK1PHLPP1ILKLMNA
Gamma-Tocopherol SCHEMBL28686334 0.99 AKT1 (0.89) AKT1PDPK1PHLPP1ILKLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16820 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746844-A1 PERSONAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2026-05-27 EP claimed
CN-122094649-A Personal care compositions 2026-05-26 CN claimed
US-12636281-B2 Dietary supplements to ameliorate dietary inadequacies related to brain health or neurodegenerative diseases, and methods to design dietary supplements NEURORESERVE INC. (US) 2026-05-26 US claimed
US-12636251-B1 Glycoside-containing aqueous formulations having a lipophilic active component Doane Technology Group LLC (US) 2026-05-26 US claimed
EP-4739143-A1 METHOD OF OBTAINING A FERMENTED OLIVE POMACE PASTE, FERMENTED OLIVE POMACE PASTE, SACCHAROMYCES CEREVISIAE AND USES THEREOF Universidade Do Porto (PT) 2026-05-13 EP claimed
CN-122005460-A Extrudate comprising vitamin A 帝斯曼知识产权资产管理有限公司 2026-05-12 CN claimed
US-20260124252-A1 Dietary Pattern Directed Nutritional Supplementation Composition and Methods for Attenuating Age-Related Cognitive Decline or Enhancing Cognitive Function NEURORESERVE INC (US) 2026-05-07 US claimed
US-12589105-B2 Human milk fortifier composition SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-31 US claimed
EP-4673231-A1 PERSONAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2026-01-07 EP claimed
US-20250312264-A1 Skin Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2025-10-09 US claimed
EP-0207158-A4 ANTI-ASTHMATIC COMPOSITION CONTAINING 8,11,14,17-EICOSATETRAENOIC ACID. RUBIN DAVID 1987-07-09 EP claimed
EP-0207158-A1 ANTI-ASTHMATIC COMPOSITION CONTAINING 8,11,14,17-EICOSATETRAENOIC ACID CENTURY LABORATORIES INC. (US) 1987-01-07 EP claimed
EP-0207735-A1 Method of manufacturing phenol-type natural antioxidants Takemoto Yushi Kabushiki Kaisha (JP) 1987-01-07 EP claimed
WO-1986003969-A1 ANTI-ASTHMATIC COMPOSITION AND METHOD USING 8,11,14,17-EICOSATETRAENOIC ACID RUBIN DAVID (US) 1986-07-17 WO claimed
EP-0187013-A2 Photoconductive imaging member XEROX CORPORATION (US) 1986-07-09 EP claimed
US-4584320-A Anti-asthmatic composition and method using 8,11,14,17-eicosatetraenoic acid RUBIN, DAVID 1986-04-22 US claimed
US-4563408-A ELECTROGRAPHY XEROX CORPORATION (US) 1986-01-07 US claimed
US-4326523-A CONTROLLED RELEASE PELLETS INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1982-04-27 US claimed
US-4212863-A ANTIFERTILITY AGENTS AKZO N.V. (NL) 1980-07-15 US claimed
US-4000276-A HUMAN SKIN KANEBO, LTD. (JA) 1976-12-28 US claimed