Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568874 | 0.90 | PPARG (0.57) | FFAR1BCHEPPARGPTGESALOX5 | |
| SCHEMBL13596190 | 0.90 | LTA4H (0.53) | BCHEKCNH2CYP4F2CYP4A11PPARG | |
| SCHEMBL3026666 | 0.88 | KDM4E (0.56) | FFAR1BCHENPC1RAB9AMAOA | |
| SCHEMBL10235885 | 0.88 | KMT2A (0.54) | FFAR1BCHEKCNH2CYP4F2CYP4A11 | |
| SCHEMBL4568905 | 0.88 | KMT2A (0.54) | FFAR1NPC1RAB9APPARGPTGES | |
| SCHEMBL24041762 | 0.87 | BCHE (0.50) | FFAR1BCHEKCNH2MAOB | |
| SCHEMBL14382693 | 0.86 | CYP2D6 (0.57) | KCNH2PPARGPPARA | |
| SCHEMBL17912866 | 0.85 | NPC1 (0.60) | FFAR1NPC1RAB9AMAOAMAOB | |
| SCHEMBL4568878 | 0.85 | PPARA (0.58) | BCHEPPARGMAOAMAOBPPARA | |
| SCHEMBL10235877 | 0.85 | PPARA (0.58) | BCHEKCNH2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |