Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 0.75 |
| ▸ | HTR1D | P28221 | 1/20 | 0.75 |
| ▸ | HTR1B | P28222 | 1/20 | 0.75 |
| ▸ | HTR2A | P28223 | 1/20 | 0.75 |
| ▸ | HTR2C | P28335 | 1/20 | 0.75 |
| ▸ | HTR1F | P30939 | 1/20 | 0.75 |
| ▸ | HTR7 | P34969 | 1/20 | 0.75 |
| ▸ | DRD3 | P35462 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13908196 | 1.00 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| Oxalic Acid SCHEMBL3962204 | 0.97 | HTR6 (0.93) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL13908161 | 0.87 | HTR6 (0.77) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL8789301 | 0.83 | HTR6 (0.77) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL8789308 | 0.83 | HTR6 (0.77) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL3153292 | 0.81 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3324172 | 0.81 | HTR6 (0.82) | HTR6 | |
| SCHEMBL3962202 | 0.80 | HTR6 (0.64) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL3138888 | 0.79 | HTR6 (0.86) | HTR6HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL8789654 | 0.77 | HTR1B (0.68) | HTR6HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | disclosed |
| EP-2036888-A1 | Naphthyl-substituted sulfonamides | Laboratorios del Dr. Esteve S.A. (ES) | 2009-03-18 | — | — | EP | disclosed |