Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.57 |
| ▸ | RXRA | P19793 | 3/20 | 0.55 |
| ▸ | RXRB | P28702 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545310 | 0.88 | EGFR (0.64) | EGFRSRCMEN1KMT2ARXRA | |
| SCHEMBL29803481 | 0.88 | EGFR (0.64) | EGFRSRCMEN1KMT2ARXRA | |
| SCHEMBL3960943 | 0.87 | NR4A2 (0.58) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL1600077 | 0.87 | MRGPRX4 (0.62) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL29556736 | 0.87 | MRGPRX4 (0.62) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL3960881 | 0.86 | LMNA (0.62) | EGFRSRCMEN1KMT2AHPGD | |
| SCHEMBL9597523 | 0.86 | MRGPRX4 (0.58) | EGFRSRCTTRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10857748 | 0.85 | MRGPRX4 (0.61) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL6811499 | 0.85 | SMN1; SMN2 (0.73) | EGFRSRCMEN1KMT2ARXRA | |
| SCHEMBL10604837 | 0.85 | EGFR (0.65) | EGFRSRCNR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124573-A | Novel cytotoxic molecules for use in cell binding molecule-drug conjugates | 杭州多禧生物科技有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-107074879-B | Novel cytotoxic molecules for use in cell binding molecule-drug conjugates | 杭州多禧生物科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| US-7589170-B1 | Synthesis of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-09-15 | — | — | US | disclosed |
| US-7589170-B1 | Synthesis of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-09-15 | — | — | US | disclosed |
| EP-1115738-A4 | SYNTHESIS OF CYCLIC PEPTIDES | UNIV QUEENSLAND (AU) | 2004-09-01 | — | — | EP | disclosed |
| EP-1115738-A1 | SYNTHESIS OF CYCLIC PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018790-A1 | SYNTHESIS OF CYCLIC PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2000-04-06 | — | — | WO | disclosed |