Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.56 |
| ▸ | CSF1R | P07333 | 3/20 | 0.56 |
| ▸ | LGMN | Q99538 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | S100B | P04271 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3543650 | 0.90 | CSF1R (0.53) | GAAMAPTHTTKDM4EMAPK1 | |
| SCHEMBL3538623 | 0.84 | GAA (0.79) | GAAMAPTHTTKDM4EMAPK1 | |
| SCHEMBL3966405 | 0.83 | CSF1R (0.55) | GAAMAPTKDM4EMAPK1CSF1R | |
| SCHEMBL3538708 | 0.80 | MAPT (0.60) | GAAMAPTMAPK1CSF1RALDH1A1 | |
| SCHEMBL27691384 | 0.79 | LGMN (0.55) | GAAMAPTHTTKDM4EMAPK1 | |
| SCHEMBL3539723 | 0.79 | LGMN (0.55) | GAAMAPTHTTKDM4EMAPK1 | |
| SCHEMBL3543649 | 0.78 | CSF1R (0.66) | GAACSF1RALDH1A1MEN1KMT2A | |
| SCHEMBL3538619 | 0.78 | GAA (0.50) | GAAMAPTHTTKDM4EMAPK1 | |
| SCHEMBL3540354 | 0.78 | LGMN (0.77) | GAAMAPTHTTKDM4EMAPK1 | |
| SCHEMBL3958578 | 0.78 | GAA (0.55) | GAAMAPTHTTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807407-B1 | AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-29 | — | — | EP | claimed |