Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 15/20 | 0.53 |
| ▸ | CCKAR | P32238 | 11/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.45 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.44 |
| ▸ | NOTCH3 | Q9UM47 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642854 | 0.85 | CCKBR (0.55) | CCKBRCCKAR | |
| SCHEMBL3968115 | 0.83 | MEN1 (0.56) | CCKBRCCKAR | |
| SCHEMBL1574481 | 0.82 | BRD4 (0.62) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL1574479 | 0.82 | BRD4 (0.62) | CCKBRCCKARBRD4BRD2BRD3 | |
| SCHEMBL641999 | 0.77 | CCKBR (0.59) | CCKBRCCKAR | |
| SCHEMBL4420909 | 0.75 | CCKBR (0.67) | CCKBRCCKAR | |
| SCHEMBL644305 | 0.74 | CCKBR (0.69) | CCKBRCCKAR | |
| SCHEMBL642831 | 0.74 | CCKBR (0.65) | CCKBRCCKAR | |
| SCHEMBL3183396 | 0.73 | CCKBR (0.48) | CCKBRCCKARNOTCH1NOTCH3 | |
| SCHEMBL3962384 | 0.73 | CCKBR (0.59) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727550-B1 | PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBITOR OF THE RSV FUSION PROTEIN | ARROW THERAPEUTICS LTD (GB) | 2009-07-29 | — | — | EP | claimed |