Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27209008 | 1.00 | ATM (0.47) | ATMGAAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7723695 | 0.85 | GAA (0.42) | ATMGAAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL22668297 | 0.82 | GSK3B (0.46) | ATMGAAHTTSLC6A4TSHR | |
| SCHEMBL16563474 | 0.80 | GSK3B (0.53) | ATMGAAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL5468294 | 0.80 | ALDH1A1 (0.45) | ATMGAAKDM4ESMN1; SMN2SLC6A4 | |
| SCHEMBL5468295 | 0.80 | ALDH1A1 (0.45) | ATMGAAKDM4ESMN1; SMN2SLC6A4 | |
| SCHEMBL27208908 | 0.80 | GAA (0.44) | GAAHTTKDM4ESMN1; SMN2SLC6A4 | |
| SCHEMBL16563473 | 0.80 | GSK3B (0.53) | ATMGAAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL28738527 | 0.80 | SMN1; SMN2 (0.66) | KDM4ESMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL27208795 | 0.80 | GAA (0.44) | GAAHTTKDM4ESMN1; SMN2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011201-A | Preparation method of amide | 南京工业大学 | 2017-08-04 | — | — | CN | claimed |
| US-20070114155-A1 | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL RAFFINAGE FRANCE (FR) | 2007-05-24 | — | — | US | claimed |
| JP-2007501701-A | — | — | 2007-02-01 | — | — | JP | claimed |
| CN-1845789-A | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL FRANCE (FR) | 2006-10-11 | — | — | CN | claimed |
| EP-1660232-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | Total France (FR) | 2006-05-31 | — | — | EP | claimed |
| WO-2005016518-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | TOTAL FRANCE (FR) | 2005-02-24 | — | — | WO | claimed |
| CN-107011201-B | A kind of preparation method of amide | 南京工业大学 | 2019-11-22 | — | — | CN | disclosed |
| CN-109824660-A | The method that rhodium catalysis arene oxidizing amination prepares the aromatic amine compounds of 2- pyridyl group substitution | 陕西师范大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-107382856-A | New multi-substituted isoquinoline derivative and its synthetic method | 江苏理工学院 | 2017-11-24 | — | — | CN | disclosed |
| CN-105037211-B | A kind of threonyl amine carbamate derivative and application | 南开大学 | 2017-08-18 | — | — | CN | disclosed |
| CN-107011201-A | Preparation method of amide | 南京工业大学 | 2017-08-04 | — | — | CN | disclosed |
| US-8535515-B2 | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL FRANCE (FR) | 2013-09-17 | — | — | US | disclosed |
| CN-1845789-B | Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof | TOTAL FRANCE | 2011-05-11 | — | — | CN | disclosed |
| WO-2005016518-A1 | HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF | TOTAL FRANCE (FR) | 2005-02-24 | — | — | WO | disclosed |
| US-5608069-A | TREATMENT OF NERVOUS SYSTEM DISORDERS WITH GAMMA-AMINOBUTYRIC ACID | NOVO NORDISK A/S (DK) | 1997-03-04 | — | — | US | disclosed |
| CN-1128990-A | N-substituted azaheterocyclic carboxylic acids and esters thereof | NOVO NORDISK AS (DK) | 1996-08-14 | — | — | CN | disclosed |
| EP-0555068-B1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1996-04-10 | — | — | EP | disclosed |
| EP-0555068-A1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1993-08-11 | — | — | EP | disclosed |
| CN-1005376-B | Herbicides containing 5- (2-chloro-4-trifluoromethylphenoxy) -2-nitro-alpha-substituted acetophenone and/or oxime derivative as active ingredient and method for eliminating undesirable weeds | 旭化成工业株式会社 | 1989-10-11 | — | — | CN | disclosed |
| CN-85109609-A | Contain the acetophenone of 5-(2-chloro-4-4-trifluoromethylphenopendant)-2-nitro-alpha-substituted and/or derivative oxime as the weed killer herbicide of active ingredient and eliminate unwanted method for weed | — | 1986-11-05 | — | — | CN | disclosed |