SCHEMBL3967039

SCHEMBL3967039

CCC(Oc1cc(Oc2ccc(CN(Cc3ccc(F)cc3F)c3cccc(NS(C)(=O)=O)c3C)cc2)ccc1Cl)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 0.78
PGR P06401 5/20 0.78
NR3C2 P08235 3/20 0.78
AR P10275 3/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3965445 0.92 NR3C1 (0.80) NR3C1PGRNR3C2AR
SCHEMBL3962634 0.88 NR3C1 (1.00) NR3C1PGRNR3C2AR
SCHEMBL7682817 0.87 NR3C1 (0.82) NR3C1PGRNR3C2AR
SCHEMBL7682813 0.86 NR3C1 (0.80) NR3C1PGRNR3C2AR
SCHEMBL3966609 0.86 NR3C1 (0.86) NR3C1PGRNR3C2AR
SCHEMBL3970745 0.85 NR3C1 (0.79) NR3C1PGRNR3C2AR
SCHEMBL3966776 0.85 NR3C1 (0.56) NR3C1PGRNR3C2AR
SCHEMBL3966775 0.85 NR3C1 (0.56) NR3C1PGRNR3C2AR
SCHEMBL3972005 0.84 NR3C1 (0.90) NR3C1PGRNR3C2AR
SCHEMBL3967227 0.83 NR3C1 (0.86) NR3C1PGRNR3C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363876-B1 GLUCOCORTICOID RECEPTOR MODULATORS KAROBIO AB (SE) 2009-07-29 EP disclosed
US-7563588-B2 Electrically non-conductive, nanoparticulate membrane AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-07-21 US disclosed
US-20070042377-A1 Biosensor AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2007-02-22 US disclosed