Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11138540 | 1.00 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL43480 | 1.00 | — | — | |
| Bicarbonate SCHEMBL6445891 | 1.00 | — | — | |
| Bicarbonate SCHEMBL27835183 | 1.00 | — | — | |
| Bicarbonate SCHEMBL31679605 | 1.00 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL6445894 | 1.00 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL1778895 | 0.93 | — | — | |
| Bicarbonate SCHEMBL1784248 | 0.93 | — | — | |
| Bicarbonate SCHEMBL21815794 | 0.93 | — | — | |
| Bicarbonate SCHEMBL21059474 | 0.93 | CA1 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777153-A | 20 (S) -10, 11-difluoro methylenedioxy camptothecine derivative and preparation method and application thereof | 浙江工业大学 | 2024-03-29 | — | — | CN | claimed |
| US-20090104121-A1 | Multi-subunit biological complexes for treatment of plaque-associated diseases | PLAXGEN, INC (US) | 2009-04-23 | — | — | US | claimed |
| WO-2009045406-A1 | MULTI-SUBUNIT BIOLOGICAL COMPLEXES FOR TREATMENT OF PLAQUE-ASSOCIATED DISEASES | PLAXGEN, INC. (US) | 2009-04-09 | — | — | WO | claimed |
| US-6193904-B1 | MIXING SEPARATELY PRECIPITATED FERROUS DICARBOXYLATE AND A SECOND METAL DICARBOXYLATE, CALCINING TO FORM THE FERRITE POWDER FOR USE IN A MICROWAVE ELEMENT | NORTHROP GRUMMAN CORPORATION | 2001-02-27 | — | — | US | claimed |
| CN-117777153-A | 20 (S) -10, 11-difluoro methylenedioxy camptothecine derivative and preparation method and application thereof | 浙江工业大学 | 2024-03-29 | — | — | CN | disclosed |
| EP-3010625-B1 | HIGHLY ACTIVE NANO IRON CATALYST FOR THE ABSORPTION OF HYDROGEN SULFIDE | NEW TECH VENTURES INC (US) | 2019-08-07 | — | — | EP | disclosed |
| US-8932558-B2 | Multi-subunit biological complexes for treatment of plaque-associated diseases | PLAXGEN INC (US) | 2015-01-13 | — | — | US | disclosed |
| US-20090104121-A1 | Multi-subunit biological complexes for treatment of plaque-associated diseases | PLAXGEN, INC (US) | 2009-04-23 | — | — | US | disclosed |
| WO-2009045406-A1 | MULTI-SUBUNIT BIOLOGICAL COMPLEXES FOR TREATMENT OF PLAQUE-ASSOCIATED DISEASES | PLAXGEN, INC. (US) | 2009-04-09 | — | — | WO | disclosed |