Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.55 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465187 | 0.80 | CNR2 (0.65) | CNR2CNR1KMT2AGRIK1 | |
| SCHEMBL3962868 | 0.80 | CNR2 (0.43) | CNR2CNR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1465749 | 0.79 | CNR2 (0.61) | CNR2CNR1KMT2AMEN1NPC1 | |
| SCHEMBL1464368 | 0.77 | CNR2 (0.76) | CNR2CNR1KMT2AMEN1 | |
| SCHEMBL1464824 | 0.75 | CNR2 (0.59) | CNR2CNR1 | |
| SCHEMBL1464953 | 0.73 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL1464492 | 0.72 | CNR2 (1.00) | CNR2CNR1KMT2AMEN1GRIK1 | |
| SCHEMBL1464599 | 0.72 | CNR2 (0.56) | CNR2CNR1 | |
| SCHEMBL1464687 | 0.71 | CNR2 (0.67) | CNR2CNR1NPC1RAB9A | |
| SCHEMBL1464328 | 0.71 | CNR2 (0.65) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |