SCHEMBL3962868

CC(C)(C(=O)Nc1ccc(C(F)(F)F)cc1)S(=O)(=O)c1ccc(Cl)cc1.CC(C)(C(=O)Nc1ccc(Cl)cc1)S(=O)(=O)c1ccc(Cl)cc1.CC(C)(C(=O)Nc1ccc2ccccc2n1)S(=O)(=O)c1ccc(Cl)cc1.CC(C)(C(=O)Nc1cccc(C(F)(F)F)c1)S(=O)(=O)c1ccc(Cl)cc1.CC(C)(C(=O)Nc1cccc(Cl)c1)S(=O)(=O)c1ccc(Cl)cc1.CC(C)(C(=O)Nc1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1.CC(C)(C(=O)Nc1ccccc1Cl)S(=O)(=O)c1ccc(Cl)cc1.CC(C)(C(=O)Nc1ccccn1)S(=O)(=O)c1ccc(Cl)cc1.CC(C)(C(=O)Nc1nc(-c2ccc(Cl)cc2)cs1)S(=O)(=O)c1ccc(Cl)cc1.CC(C)(C)c1ccccc1NC(=O)C(C)(C)S(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CNR2	P34972	6/20	0.43

▸	MAPT	P10636	8/20	0.39

▸	KDM4E	B2RXH2	4/20	0.39

▸	MEN1	O00255	3/20	0.39

▸	KMT2A	Q03164	3/20	0.39

▸	CNR1	P21554	3/20	0.38

▸	MAPK1	P28482	1/20	0.37

▸	SMN1; SMN2	Q16637	2/20	0.36

▸	VCP	P55072	1/20	0.36

▸	NPSR1	Q6W5P4	2/20	0.36

▸	KDM1A	O60341	3/20	0.36

▸	POLB	P06746	1/20	0.36

▸	USP2	O75604	1/20	0.34

▸	USP8	P40818	1/20	0.34

▸	MPL	P40238	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3967399	0.80	CNR2 (0.55)	CNR2MEN1KMT2ACNR1SMN1; SMN2
SCHEMBL3963567	0.79	CNR2 (0.50)	CNR2MAPTKDM4EMEN1KMT2A
SCHEMBL4081933	0.69	CNR2 (0.33)	CNR2MAPTKDM4EMEN1KMT2A
SCHEMBL1465740	0.66	ABL1 (0.62)	CNR2MAPTMEN1KMT2ACNR1
SCHEMBL4016147	0.66	MAPT (0.41)	CNR2MAPTKDM4EMEN1KMT2A
SCHEMBL3961423	0.66	CNR2 (0.48)	CNR2MAPTKDM4EMEN1KMT2A
SCHEMBL1464404	0.66	KDM1A (0.60)	CNR2MAPTMEN1KMT2ACNR1
SCHEMBL1464341	0.66	ALDH1A1 (0.58)	CNR2MAPTMEN1KMT2ACNR1
SCHEMBL1465202	0.66	PAX8 (0.61)	CNR2MEN1KMT2ACNR1KDM1A
SCHEMBL1463680	0.66	CNR2 (0.64)	CNR2CNR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2081905-A2	SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR	Boehringer Ingelheim International GmbH (DE)	2009-07-29	—	—	EP	claimed
WO-2008014199-A2	SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR	BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE)	2008-01-31	—	—	WO	claimed