Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 16/20 | 0.51 |
| ▸ | MMP2 | P08253 | 15/20 | 0.51 |
| ▸ | MMP14 | P50281 | 14/20 | 0.51 |
| ▸ | MMP9 | P14780 | 13/20 | 0.51 |
| ▸ | MMP3 | P08254 | 11/20 | 0.51 |
| ▸ | MMP8 | P22894 | 11/20 | 0.51 |
| ▸ | MMP1 | P03956 | 10/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967700 | 0.89 | MMP2 (0.47) | MMP13MMP2MMP14MMP9MMP3 | |
| SCHEMBL3961456 | 0.84 | MMP2 (0.46) | MMP13MMP2MMP14MMP9MMP3 | |
| SCHEMBL1464356 | 0.83 | MMP2 (0.65) | MMP13MMP2MMP14MMP9MMP3 | |
| SCHEMBL1464643 | 0.81 | MMP2 (0.57) | MMP13MMP2MMP14MMP9MMP3 | |
| SCHEMBL3964990 | 0.80 | MMP2 (0.48) | MMP13MMP2MMP14MMP9MMP3 | |
| SCHEMBL3961452 | 0.79 | MMP2 (0.45) | MMP13MMP2MMP14MMP9MMP3 | |
| SCHEMBL3964989 | 0.77 | MMP2 (0.47) | MMP13MMP2MMP14MMP9MMP3 | |
| SCHEMBL1464281 | 0.74 | MMP2 (0.51) | MMP13MMP2MMP14MMP9MMP3 | |
| SCHEMBL1464750 | 0.73 | SMN1; SMN2 (0.51) | MMP13MMP2MMP14MMP9MMP3 | |
| SCHEMBL12095680 | 0.72 | GCK (0.46) | MMP13MMP2MMP14MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |