Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969346 | 0.90 | MEN1 (0.32) | — | |
| SCHEMBL3968452 | 0.82 | PTGDR2 (0.46) | PTGDR2PTGDR | |
| SCHEMBL3971980 | 0.82 | PTGDR2 (0.36) | PTGDR2PTGDR | |
| SCHEMBL3971882 | 0.78 | PTGDR2 (0.46) | PTGDR2PTGDR | |
| SCHEMBL3964681 | 0.75 | PTGDR2 (0.46) | PTGDR2PTGDR | |
| SCHEMBL3967751 | 0.73 | PTGDR2 (0.39) | PTGDR2PTGDR | |
| SCHEMBL3968952 | 0.73 | PTGDR2 (0.43) | PTGDR2PTGDR | |
| SCHEMBL3970488 | 0.73 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL3974573 | 0.72 | PTGDR2 (0.41) | PTGDR2 | |
| SCHEMBL3968057 | 0.72 | PTGDR2 (0.59) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |