Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967762 | 0.90 | PTGDR2 (0.38) | — | |
| SCHEMBL3967751 | 0.83 | PTGDR2 (0.39) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL3970488 | 0.83 | SMN1; SMN2 (0.32) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL3968018 | 0.79 | PTGDR2 (0.39) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL3962109 | 0.77 | PTGDR2 (0.39) | MEN1KMT2AMAPTLMNATSHR | |
| SCHEMBL3969206 | 0.76 | SLC6A4 (0.37) | MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL3973410 | 0.74 | PTGDR2 (0.33) | MEN1KMT2ASMN1; SMN2SLC34A1 | |
| SCHEMBL3969463 | 0.74 | PTGDR2 (0.47) | MEN1KMT2AMAPT | |
| SCHEMBL3968452 | 0.73 | PTGDR2 (0.46) | — | |
| SCHEMBL3577485 | 0.73 | TSHR (0.38) | MEN1KMT2ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |