Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114422 | 1.00 | TSHR (0.50) | TSHRTRPA1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL28792130 | 0.87 | TRPA1 (0.43) | TSHRTRPA1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL1201089 | 0.87 | TRPA1 (0.43) | TSHRTRPA1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL4437005 | 0.87 | TSHR (0.43) | TSHRTRPA1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL27854889 | 0.87 | TSHR (0.43) | TSHRTRPA1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL12919553 | 0.85 | TSHR (0.52) | TSHRTRPA1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL3685810 | 0.85 | TRPA1 (0.52) | TSHRTRPA1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL27539710 | 0.83 | TSHR (0.48) | TSHRTRPA1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL2162532 | 0.83 | TSHR (0.48) | TSHRTRPA1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL198464 | 0.81 | TSHR (0.46) | TSHRTRPA1ALDH1A1SMN1; SMN2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| CN-101899026-B | Intermediates for the preparation of analogs of halichondrin B | 卫材R&D管理有限公司 | 2016-08-03 | — | — | CN | claimed |
| CN-104530417-A | Multifunctional H-type polyethylene glycol derivative and preparation method thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-110088113-A | Composition and method for phosphoramidite and oligonucleotide synthesis | 波涛生命科学有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-110023308-A | N-ACYLETHANOLAMIDE DERIVATIVES AND USES THEREOF | 卡诺有限责任公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109563131-A | Chiral peptide | 卡诺有限责任公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109563515-A | Compound and the method for adjusting RNA function | 阿拉基斯医疗公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109180615-A | Intermediates for the preparation of analogs of halichondrin B | 卫材R&D管理有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-108997267-A | Intermediates for the preparation of analogs of halichondrin B | 卫材R&D管理有限公司 | 2018-12-14 | — | — | CN | disclosed |
| CN-108778345-A | Compounds and methods for treating RNA-mediated diseases | 阿拉基斯医疗公司 | 2018-11-09 | — | — | CN | disclosed |
| US-5025034-A | Thromboxane inhibitors | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-06-18 | — | — | US | disclosed |
| US-4945106-A | Prostaglandins | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-07-31 | — | — | US | disclosed |
| EP-0111955-B1 | PROSTAGLANDIN INTERMEDIATES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-09-17 | — | — | EP | disclosed |
| US-4596823-A | Prostaglandins | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-06-24 | — | — | US | disclosed |
| EP-0043292-B1 | PROSTAGLANDINS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-01-15 | — | — | EP | disclosed |
| EP-0111955-A1 | Prostaglandin intermediates | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-06-27 | — | — | EP | disclosed |
| WO-1982000142-A1 | PROSTAGLANDINS | JONES R | 1982-01-21 | — | — | WO | disclosed |
| EP-0043292-A2 | Prostaglandins | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-01-06 | — | — | EP | disclosed |