Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 11/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448715 | 0.84 | CDK2 (0.41) | CA2CA1CA9CA12CDK2 | |
| SCHEMBL2724413 | 0.80 | CA2 (0.48) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL27643670 | 0.80 | CA2 (0.48) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL6062879 | 0.80 | CA2 (0.45) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL5514013 | 0.79 | CA2 (0.41) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL27985077 | 0.78 | CA2 (0.44) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL31344740 | 0.76 | BID (0.46) | CA2LIPGSMN1; SMN2CA1CA9 | |
| SCHEMBL21439079 | 0.76 | CA2 (0.41) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL11157738 | 0.76 | PTGES2 (0.44) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL2066500 | 0.75 | CDK2 (0.44) | CA2CA1CA9CA12CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046416-A1 | ANILINOPYRIMIDINES AS JAK KINASE INHIBITORS | TARGEGEN INC. (US) | 2009-04-09 | — | — | WO | disclosed |