Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747186 | 0.83 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL28384325 | 0.78 | CA1 (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL325041 | 0.77 | CA1 (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10151017 | 0.75 | CA1 (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL4013920 | 0.73 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28557959 | 0.72 | TSHR (0.51) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29679791 | 0.72 | TSHR (0.51) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28438444 | 0.72 | TSHR (0.51) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29679915 | 0.72 | TSHR (0.51) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27085681 | 0.72 | TSHR (0.51) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046016-A1 | FLUOROPOLYMER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-09 | — | — | WO | disclosed |