Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACR | P10323 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464777 | 0.76 | MEN1 (0.49) | KMT2ARAB9AMEN1GRIK1CNR2 | |
| SCHEMBL1463942 | 0.71 | MAPK14 (0.50) | MAPK14CNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3963561 | 0.71 | MAPK14 (0.34) | MAPK14 | |
| SCHEMBL1465189 | 0.67 | MAPK14 (0.46) | MAPK14KMT2ARAB9AMEN1CNR2 | |
| SCHEMBL1465822 | 0.67 | CNR2 (0.50) | MAPK14KMT2ARAB9AMEN1CNR2 | |
| SCHEMBL1465091 | 0.64 | CNR2 (0.41) | MAPK14KMT2ARAB9AMEN1CNR2 | |
| SCHEMBL1466268 | 0.62 | MAPK14 (0.47) | MAPK14RAB9ACNR2ALDH1A1NPC1 | |
| SCHEMBL4014217 | 0.62 | CNR2 (0.57) | MAPK14CNR2MMP8LMNAKDM4E | |
| SCHEMBL1464666 | 0.62 | CNR2 (0.43) | MAPK14KMT2ARAB9AMEN1CNR2 | |
| SCHEMBL1464909 | 0.62 | CNR2 (0.57) | KMT2AMEN1GRIK1CNR2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |