SCHEMBL3963561

CC(C)(C(=O)Nc1cccc2ccccc12)S(=O)(=O)c1ccc(Cl)cc1F.CC(C)(C)Cc1cc(NC(=O)C(C)(C)S(=O)(=O)c2ccc(Cl)cc2F)on1.CCCc1cc(NC(=O)C(C)(CNC(=O)C(C)(Cc2nc(C3CCCCC3)cs2)S(=O)(=O)c2ccc(Cl)cc2F)S(=O)(=O)c2ccc(Cl)cc2F)on1

nearest known ligand 0.34

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK14	Q16539	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1465189	0.76	MAPK14 (0.46)	MAPK14
SCHEMBL1464666	0.72	CNR2 (0.43)	MAPK14
SCHEMBL3963813	0.72	RORC (0.46)	—
SCHEMBL1463942	0.72	MAPK14 (0.50)	MAPK14
SCHEMBL3968553	0.71	MAPK14 (0.35)	MAPK14
SCHEMBL4081933	0.70	CNR2 (0.33)	—
SCHEMBL3959989	0.69	MAPK14 (0.43)	MAPK14
SCHEMBL1464777	0.69	MEN1 (0.49)	—
SCHEMBL1464626	0.68	TMIGD3 (0.50)	—
SCHEMBL4081939	0.68	CNR2 (0.31)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2081905-A2	SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR	Boehringer Ingelheim International GmbH (DE)	2009-07-29	—	—	EP	claimed
WO-2008014199-A2	SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR	BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE)	2008-01-31	—	—	WO	claimed