Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25525 | 0.92 | HPGD (0.56) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL16198946 | 0.89 | HPGD (0.61) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL12031119 | 0.89 | HPGD (0.61) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL12150640 | 0.89 | HPGD (0.61) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL26515 | 0.89 | HPGD (0.61) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL16360143 | 0.89 | HPGD (0.61) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL12300426 | 0.89 | HPGD (0.61) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL18512866 | 0.89 | HPGD (0.61) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL3713950 | 0.89 | HPGD (0.61) | HINT1HPGDNT5EADORA2AADORA2B | |
| SCHEMBL222316 | 0.89 | HPGD (0.61) | HINT1HPGDNT5EADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009043096-A1 | IMPROVED METHOD FOR MUTAGENESIS | ARANA THERAPEUTICS (VIC) PTY LTD (AU) | 2009-04-09 | — | — | WO | disclosed |