SCHEMBL3969269

SCHEMBL3969269

C=CC(=O)N[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4412906 0.77
SCHEMBL2590452 0.74
SCHEMBL371204 0.74
SCHEMBL8079046 0.70
SCHEMBL324882 0.69
SCHEMBL25369963 0.67 TSHR (0.53)
SCHEMBL9873761 0.67
SCHEMBL7165464 0.67
SCHEMBL26217 0.67
SCHEMBL22042664 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101300241-A Piperazine derivatives as antimalarial agents ACTELION PHARMACEUTICALS LTD (CH) 2008-11-05 CN claimed
CN-105408325-B cyanotriazole compounds 大塚制药株式会社 2019-10-22 CN disclosed
CN-109890918-A hydrophilic coating composition 株式会社LG化学 2019-06-14 CN disclosed
CN-105408325-A Cyanotriazole compounds OTSUKA PHARMA CO LTD 2016-03-16 CN disclosed
US-7497970-B2 Chiral agent for liquid crystal, liquid crystal composition and polymer, as well as filter for optical recording medium, optical recording medium and color filter liquid for crystal FUJIFILM CORPORATION (JP) 2009-03-03 US disclosed
CN-101300241-A Piperazine derivatives as antimalarial agents ACTELION PHARMACEUTICALS LTD (CH) 2008-11-05 CN disclosed
US-20070228325-A1 Chiral agent for liquid crystal, liquid crystal composition and polymer, as well as filter for optical recording medium, optical recording medium and color filter liquid for crystal FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
EP-0944653-A4 POLYMERIC COUPLING AGENTS FOR THE ADHESION OF MACROMOLECULAR MATERIALS AND METAL SUBSTRATES VERNAY LABORATORIES (US) 2004-10-13 EP disclosed
EP-0944653-A1 POLYMERIC COUPLING AGENTS FOR THE ADHESION OF MACROMOLECULAR MATERIALS AND METAL SUBSTRATES VERNAY LABORATORIES, INC. (US) 1999-09-29 EP disclosed
US-5882799-A COUPLING AGENTS WHICH INCORPORATE WITHIN THEIR STRUCTURES CO-VULCANIZABLE GROUPS SUCH AS ALKENYL, EPOXIDE, ACRYLATE AND/OR ACRYLAMIDE, AND METAL-COMPLEXING GROUPS SUCH AS CARBOXYLIC, OXIME, AMINE, HYDROXAMIC AND/OR IMINODIACETIC VERNAY LABORATORIES, INC. (US) 1999-03-16 US disclosed
WO-1998027120-A1 POLYMERIC COUPLING AGENTS FOR THE ADHESION OF MACROMOLECULAR MATERIALS AND METAL SUBSTRATES VERNAY LABORATORIES, INC. (US) 1998-06-25 WO disclosed
EP-0232327-B1 SULFURIZED COMPOSITIONS, AND ADDITIVE CONCENTRATES, LUBRICATING COMPOSITIONS,METAL WORKING LUBRICANTS AND ASPHALT COMPOSITIONS CONTAINING SAME The Lubrizol Corporation (US) 1990-10-03 EP disclosed
US-4740322-A Sulfur-containing compositions, and additive concentrates, lubricating oils, metal working lubricants and asphalt compositions containing same THE LUBRIZOL CORPORATION (US) 1988-04-26 US disclosed
EP-0232327-A1 SULFURIZED COMPOSITIONS, AND ADDITIVE CONCENTRATES, LUBRICATING COMPOSITIONS,METAL WORKING LUBRICANTS AND ASPHALT COMPOSITIONS CONTAINING SAME. LUBRIZOL CORP (US) 1987-08-19 EP disclosed
WO-1987000833-A1 SULFUR-CONTAINING COMPOSITIONS, AND ADDITIVE CONCENTRATES, LUBRICATING OILS, METAL WORKING LUBRICANTS AND ASPHALT COMPOSITIONS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1987-02-12 WO disclosed