⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969269 | 0.77 | — | — | |
| SCHEMBL371204 | 0.74 | — | — | |
| SCHEMBL2590452 | 0.74 | — | — | |
| SCHEMBL8079046 | 0.70 | — | — | |
| SCHEMBL25369963 | 0.67 | TSHR (0.53) | — | |
| SCHEMBL9873761 | 0.67 | — | — | |
| SCHEMBL7165464 | 0.67 | — | — | |
| SCHEMBL26217 | 0.67 | — | — | |
| SCHEMBL692572 | 0.67 | — | — | |
| SCHEMBL11328913 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1545428-B1 | PROCESS FOR DECREASING AGGREGATE LEVELS OF PEGYLATED PROTEIN | PHARMACIA CORP (US) | 2009-12-30 | — | — | EP | disclosed |
| US-7470779-B2 | Process for decreasing aggregate levels of pegylated protein | PFIZER INC. (US) | 2008-12-30 | — | — | US | disclosed |
| US-20060157647-A1 | Multidimensional liquid chromatography/spectrometry | BECTON, DICKINSON AND COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
| EP-1545428-A4 | PROCESS FOR DECREASING AGGREGATE LEVELS OF PEGYLATED PROTEIN | PHARMACIA CORP (US) | 2006-03-01 | — | — | EP | disclosed |
| EP-1545428-A2 | PROCESS FOR DECREASING AGGREGATE LEVELS OF PEGYLATED PROTEIN | Pharmacia Corporation (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20050085631-A1 | Process for decreasing aggregate levels of pegylated protein | PHARMACIA CORPORATION (US) | 2005-04-21 | — | — | US | disclosed |
| WO-2004026251-A2 | PROCESS FOR DECREASING AGGREGATE LEVELS OF PEGYLATED PROTEIN | PHARMACIA CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |