Piperonyl Butoxide

Piperonyl Butoxide

SCHEMBL39695

CCCCOCCOCCOCc1cc2c(cc1CCC)OCO2.[Zr]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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The experimentally established mechanism targets of Piperonyl Butoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.97
ALDH1A1 P00352 4/20 0.97
TSHR P16473 1/20 0.97
HPGD P15428 2/20 0.44
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
CYP1A2 P05177 3/20 0.37
CYP2D6 P10635 3/20 0.37
CYP2C19 P33261 3/20 0.37
CYP2C9 P11712 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
HTT P42858 2/20 0.34
MAOB P27338 2/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperonyl Butoxide SCHEMBL16105717 1.00 CYP3A4 (0.97) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL11589014 0.99 CYP3A4 (0.94) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL11588274 0.99 CYP3A4 (0.94) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL29386186 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
SCHEMBL9958244 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL6561910 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL5490 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL1517385 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL104661 0.97 CYP3A4 (0.97) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL1925871 0.97 CYP3A4 (0.97) CYP3A4ALDH1A1TSHRHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3664 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698701-A1 A PARTICLE MEDIATED ANODISING PROCESS FOR WHITE ANODISED SURFACES Cirrus Materials Science Limited (NZ) 2026-02-25 EP claimed
EP-4652221-A1 HIGH FLOW POLYSTYRENE RESINS, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2025-11-26 EP claimed
EP-4652222-A1 POLYSTYRENE FOAMS WITH A FLUOROPOLYMER ADDITIVE, COMPOSITIONS THEREOF AND METHODS OF MAKING SHPP Global Technologies B.V. (NL) 2025-11-26 EP claimed
EP-4642759-A1 PROCESS FOR TREATING KERATIN FIBRES USING AT LEAST ONE OIL BEARING ACETOACETATE FUNCTIONS L'OREAL (FR) 2025-11-05 EP claimed
EP-4642757-A1 PROCESS FOR TREATING KERATIN MATERIALS USING AT LEAST ONE OIL BEARING ACETOACETATE FUNCTIONS AND AT LEAST ONE CROSSLINKING AGENT L'OREAL (FR) 2025-11-05 EP claimed
US-12414474-B2 Methods of forming piezoelectric materials, piezoelectric devices, and associated tooling and systems BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2025-09-09 US claimed
US-20250222517-A1 METHOD FOR MANUFACTURING A TIMEPIECE OR JEWELLERY COMPONENT, AND SAID TIMEPIECE OR JEWELLERY COMPONENT PATEK PHILIPPE SA GENEVE (CH) 2025-07-10 US claimed
CN-117945668-B Thin film for inhibiting breakage of thin glass and preparation method thereof 中建材玻璃新材料研究院集团有限公司 2025-05-20 CN claimed
US-12291661-B2 Quantum dot structure, method for producing a quantum dot structure, and light emitting device OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2025-05-06 US claimed
CN-119674007-A Method for coating sodium ion layered oxide positive electrode material by wet method 南京航空航天大学 2025-03-21 CN claimed
US-5340908-A Process for the preparation of aromatic polyesters COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1994-08-23 US claimed
US-5271797-A Method for patterning metal oxide thin film ROHM CO., LTD. (JP) 1993-12-21 US claimed
EP-0488135-A2 Bulk polymerizable reaction solutions NIPPON ZEON CO., LTD. (JP) 1992-06-03 EP claimed
EP-0298408-B1 METHOD FOR PREPARING NORBORNENE STRUCTURE COMPOUND NIPPON OIL CO. LTD. (JP) 1991-12-18 EP claimed
US-5064690-A Method for coating surface of inactive granules AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1991-11-12 US claimed
US-4891456-A Method for preparing norbornene structure compound NIPPON OIL CO., LTD. (JP) 1990-01-02 US claimed
EP-0298408-A1 Method for preparing norbornene structure compound NIPPON OIL CO. LTD. (JP) 1989-01-11 EP claimed
US-4789653-A CONCURRENT HYDROLYSIS OF ZIRCONIUM AND TITANIUM ALKOXIDES; LEAD AND LANTHANUM ACETATE AND NITRATE PRECIPITATION MITSUBISHI MINING AND CEMENT CO., LTD. (JP) 1988-12-06 US claimed
US-4703020-A Process for the production of jewelling and ornamental material KYOCERA CORPORATION (JP) 1987-10-27 US claimed
EP-0237640-A2 Method for production of ceramic composition MITSUBISHI MINING & CEMENT CO., LTD. (JP) 1987-09-23 EP claimed