SCHEMBL3969656

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3902823	0.89	EGFR (0.77)	EGFRERBB2
	SCHEMBL5922745	0.88	EGFR (0.76)	EGFRERBB2
	SCHEMBL6486502	0.86	EGFR (0.78)	EGFRERBB2MEN1PIK3C2BMAP2K7
	SCHEMBL3898890	0.85	EGFR (1.00)	EGFRERBB2
	SCHEMBL3904678	0.83	EGFR (0.77)	EGFRERBB2
	SCHEMBL3971200	0.82	EGFR (0.76)	EGFRERBB2
	SCHEMBL2098912	0.80	EGFR (0.83)	EGFRERBB2MEN1PIK3C2BMAP2K7
	Lapatinib SCHEMBL29464189	0.80	EGFR (1.00)	EGFRERBB2MEN1PIK3C2BMAP2K7
	Lapatinib SCHEMBL29351024	0.80	EGFR (1.00)	EGFRERBB2MEN1PIK3C2BMAP2K7
	SCHEMBL14264605	0.80	EGFR (0.90)	EGFRERBB2MEN1PIK3C2BMAP2K7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.