SCHEMBL3969711

SCHEMBL3969711

O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@]2(O)CO)c(=O)[nH]1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 2/20 0.60
SLC28A1 O00337 1/20 0.60
SLC28A2 O43868 1/20 0.60
SLC28A3 Q9HAS3 1/20 0.60
P2RY2 P41231 5/20 0.48
P2RY4 P51582 2/20 0.48
POLA1 P09884 1/20 0.45
P2RY14 Q15391 4/20 0.43
PDE4D Q08499 1/20 0.43
PDE3A Q14432 1/20 0.43
P2RY6 Q15077 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6271158 0.93 SLC29A1 (0.59) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL5420938 0.91 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL20830177 0.91 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL19352333 0.91 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL15075226 0.91 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL19352334 0.91 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL19352335 0.91 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL14405971 0.91 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL5849954 0.89 SLC29A1 (0.54) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL31210149 0.89 SLC29A1 (0.54) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009043096-A1 IMPROVED METHOD FOR MUTAGENESIS ARANA THERAPEUTICS (VIC) PTY LTD (AU) 2009-04-09 WO disclosed