SCHEMBL5849954

SCHEMBL5849954

CCC[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 2/20 0.54
SLC28A1 O00337 1/20 0.54
SLC28A2 O43868 1/20 0.54
SLC28A3 Q9HAS3 1/20 0.54
P2RY2 P41231 6/20 0.47
P2RY4 P51582 3/20 0.47
POLA1 P09884 1/20 0.42
P2RY14 Q15391 3/20 0.40
PDE4D Q08499 1/20 0.39
PDE3A Q14432 1/20 0.39
P2RY6 Q15077 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15075226 0.90 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL14405971 0.90 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL3969711 0.89 SLC29A1 (0.60) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL6271158 0.88 SLC29A1 (0.59) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
Succinic Acid SCHEMBL992636 0.86 SLC28A1 (0.45) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL19352334 0.85 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL20830177 0.85 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL5420938 0.85 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL19352333 0.85 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2
SCHEMBL19352335 0.85 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7071311-B2 Antibodies having specificity for 2′-C-allyl nucleic acids SIRNA THERAPEUTICS, INC. (US) 2006-07-04 US disclosed
US-20050042632-A1 Antibodies having specificity for nucleic acids SIRNA THERAPEUTICS, INC. (US) 2005-02-24 US disclosed
US-20030228590-A1 Antibodies having specificity for nucleic acids SIRNA THERAPEUTICS, INC. 2003-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050042632-A1 Antibodies having specificity for nucleic acids SNRPE, RNASE1, FCGR2A SLC29A1 58/4885SLC28A1 507/4885SLC28A2 632/4885
US-20030228590-A1 Antibodies having specificity for nucleic acids DUT, NSUN3, DNASE1L3 SLC29A1 19/4885SLC28A1 320/4885SLC28A2 328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.