Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.61 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 5/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962721 | 0.94 | CNR2 (0.62) | CNR2GRM5CNR1MAPK14LMNA | |
| SCHEMBL1464871 | 0.87 | CNR2 (0.55) | CNR2GRM5CNR1RORCACVR1 | |
| SCHEMBL1465546 | 0.87 | CNR2 (0.78) | CNR2CNR1MAPK14LMNAPHGDH | |
| SCHEMBL3964008 | 0.85 | CNR2 (0.46) | CNR2GRM5CNR1RORCACVR1 | |
| SCHEMBL3966606 | 0.85 | CNR2 (0.46) | CNR2GRM5CNR1MAPK14RORC | |
| SCHEMBL3965012 | 0.82 | MAPT (0.50) | CNR2GRM5CNR1LMNAPHGDH | |
| SCHEMBL1463951 | 0.82 | CNR2 (0.67) | CNR2CNR1MAPK14LMNAMAPK13 | |
| SCHEMBL1464304 | 0.81 | CNR2 (0.50) | CNR2GRM5CNR1RORCACVR1 | |
| SCHEMBL1464598 | 0.81 | CNR2 (0.78) | CNR2MAPK14LMNANTRK1MAPK13 | |
| SCHEMBL3969890 | 0.80 | CNR2 (0.47) | CNR2CNR1MAPK14RORCPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |