Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153091 | 0.85 | CYP2C19 (0.40) | CNR2CYP3A4CYP2C9CYP2C19PLA2G4B | |
| SCHEMBL38879 | 0.84 | PLK1 (0.39) | RARBPTPN11CNR2PLK1THRA | |
| SCHEMBL30787100 | 0.84 | RARB (0.43) | RARBPTPN11CNR2PLK1THRA | |
| SCHEMBL7114762 | 0.83 | CNR2 (0.36) | PTPN11CNR2PPARGPLA2G4BPPARA | |
| SCHEMBL4581126 | 0.81 | ADORA3 (0.39) | PTPN11CNR2TSHR | |
| SCHEMBL887949 | 0.81 | CNR2 (0.46) | RARBPTPN11CNR2CYP2C9CYP2C19 | |
| SCHEMBL16985037 | 0.81 | CNR2 (0.46) | RARBPTPN11CNR2CYP2C9CYP2C19 | |
| SCHEMBL29353180 | 0.81 | CNR2 (0.46) | RARBPTPN11CNR2CYP2C9CYP2C19 | |
| SCHEMBL5081657 | 0.81 | PLK1 (0.40) | PTPN11CNR2PLK1PPARGPLA2G4B | |
| SCHEMBL10090875 | 0.81 | PTPN11 (0.52) | RARBPTPN11CNR2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476699-B2 | Amino- and hydroxysubstituted triphenyl-s-triazines as stabilizers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20070274933-A1 | Amino- and hydroxysubstituted triphenyl-S-triazines as stabilizers | REINEHR DIETER | 2007-11-29 | — | — | US | disclosed |
| US-20040049052-A1 | Benzophenone uv-absorbers with heterocyclic substituents | CIBA SPECIALTY CHEMICALS CORP. | 2004-03-11 | — | — | US | disclosed |
| EP-1351943-A1 | BENZOPHENONE UV-ABSORBERS WITH HETEROCYCLIC SUBSTITUENTS | Ciba SC Holding AG (CH) | 2003-10-15 | — | — | EP | disclosed |
| EP-1021421-B1 | AMINO- AND HYDROXYSUBSTITUTED TRIPHENYL-S-TRIAZINES AS STABILIZERS | CIBA SC HOLDING AG (CH) | 2003-10-01 | — | — | EP | disclosed |
| EP-1322640-A1 | HETEROARYL SUBSTITUTED HYDROXYPHENYLTRIAZINE UV-ABSORBERS | Ciba SC Holding AG (CH) | 2003-07-02 | — | — | EP | disclosed |
| US-20020165298-A1 | Amino- and hydroxysubstituted triphenyl-s-triazines as stabilizers | REINEHR DIETER (DE) | 2002-11-07 | — | — | US | disclosed |
| WO-2002048118-A1 | BENZOPHENONE UV-ABSORBERS WITH HETEROCYCLIC SUBSTITUENTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |
| WO-2002028854-A1 | HETEROARYL SUBSTITUTED HYDROXYPHENYLTRIAZINE UV-ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-04-11 | — | — | WO | disclosed |
| EP-1021421-A1 | AMINO- AND HYDROXYSUBSTITUTED TRIPHENYL-S-TRIAZINES AS STABILIZERS | Ciba SC Holding AG (CH) | 2000-07-26 | — | — | EP | disclosed |
| WO-1997036880-A1 | AMINO- AND HYDROXYSUBSTITUTED TRIPHENYL-S-TRIAZINES AS STABILIZERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049052-A1 | Benzophenone uv-absorbers with heterocyclic substituents | TRPC1, C1S, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | RARB 2822/4885PTPN11 4664/4885CNR2 465/4885 |
| US-20070274933-A1 | Amino- and hydroxysubstituted triphenyl-S-triazines as stabilizers | AHR, HRH4, HRH2 | RARB 2933/4885PTPN11 2768/4885CNR2 105/4885 |
| US-20020165298-A1 | Amino- and hydroxysubstituted triphenyl-s-triazines as stabilizers | CCNL2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AHR | RARB 2807/4885PTPN11 2968/4885CNR2 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.