Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 17/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351616 | 1.00 | HSD11B1 (0.55) | HSD11B1CYP2D6NPY5R | |
| SCHEMBL349531 | 0.88 | HSD11B1 (0.68) | HSD11B1CYP2D6 | |
| SCHEMBL350456 | 0.88 | HSD11B1 (0.68) | HSD11B1CYP2D6 | |
| SCHEMBL350662 | 0.85 | HSD11B1 (0.64) | HSD11B1CYP2D6NPY5R | |
| SCHEMBL350261 | 0.85 | HSD11B1 (0.64) | HSD11B1CYP2D6NPY5R | |
| SCHEMBL350962 | 0.84 | HSD11B1 (0.52) | HSD11B1CYP2D6NPY5R | |
| SCHEMBL349642 | 0.83 | HSD11B1 (0.75) | HSD11B1CYP2D6NPY5R | |
| SCHEMBL349822 | 0.83 | HSD11B1 (0.66) | HSD11B1CYP2D6NPY5R | |
| SCHEMBL349873 | 0.83 | HSD11B1 (0.59) | HSD11B1CYP2D6NPY5R | |
| SCHEMBL351074 | 0.83 | HSD11B1 (0.59) | HSD11B1CYP2D6NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756063-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | disclosed |