Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | MAOB | P27338 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | P4HB | P07237 | 1/20 | 0.67 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.66 |
| ▸ | KRAS | P01116 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.64 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.64 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970547 | 1.00 | F3 (0.69) | F3MAPTMAOBMEN1ALDH1A1 | |
| SCHEMBL15304468 | 0.85 | F3 (0.74) | F3MAPTMAOBMEN1ALDH1A1 | |
| SCHEMBL4462407 | 0.85 | ALDH1A1 (0.56) | MAPTMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL4462409 | 0.85 | ALDH1A1 (0.56) | MAPTMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL13764738 | 0.85 | MAOB (0.69) | MAPTMAOBALDH1A1KMT2ARAB9A | |
| SCHEMBL13359041 | 0.84 | MAPT (0.66) | F3MAPTMAOBMEN1KMT2A | |
| SCHEMBL2598005 | 0.83 | MAOB (0.51) | MAOBMCL1 | |
| SCHEMBL2598006 | 0.83 | MAOB (0.51) | MAOBMCL1 | |
| SCHEMBL29151956 | 0.83 | TTR (0.59) | — | |
| SCHEMBL29151961 | 0.83 | TTR (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566737-B2 | Combinations of substituted 1,3-diphenylprop-2-en-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2009-07-28 | — | — | US | disclosed |
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | PSEN1, BACE1, PSEN2 | F3 2492/4885MAPT 133/4885MAOB 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.