⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019230 | 0.79 | — | — | |
| SCHEMBL7112610 | 0.73 | CES2 (0.37) | — | |
| SCHEMBL4965257 | 0.73 | — | — | |
| SCHEMBL27173489 | 0.69 | — | — | |
| SCHEMBL1932050 | 0.69 | — | — | |
| SCHEMBL5388382 | 0.69 | — | — | |
| SCHEMBL14771979 | 0.69 | — | — | |
| SCHEMBL10841225 | 0.67 | — | — | |
| SCHEMBL1931623 | 0.67 | — | — | |
| SCHEMBL27417148 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112254-B1 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PROD INC (US) | 2013-02-27 | — | — | EP | disclosed |
| US-7524942-B2 | Labeled nucleotide composition | AGILENT TECHNOLOGIES, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080124708-A1 | Labeled nucleotide composition | AGILENT TECHNOLOGIES, INC. | 2008-05-29 | — | — | US | disclosed |
| EP-1112254-A4 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PROD INC (US) | 2005-03-16 | — | — | EP | disclosed |
| US-6437141-B2 | FOR LABELING TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-20010020098-A1 | For labeling target molecules | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-09-06 | — | — | US | disclosed |
| EP-1112254-A2 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN Life Science Products, Inc. (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6224644-B1 | CYANINE DYES INCLUDES FREE OR PROTECTED THIOL, AMINE OR HYDROXY SUBSTITUENT CAPABLE OF REACTING WITH A TARGET MOLECULE THROUGH A NEUCLOPHILIC DISPLACEMENT, USEFUL IN LABELING A VARIETY OF TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6204389-B1 | DEBLOCKING; NUCLEOPHILIC DISPLACEMENT | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6197956-B1 | FLUORESCENT BENZIMIDAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, BENZOTHIAZINE, BENZOXAZINE AND QUINOLINE DYES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-06 | — | — | US | disclosed |
| WO-2000063296-A2 | CYANINE DYES AND SYNTHESIS METHODS THEREOF | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-10-26 | — | — | WO | disclosed |
| US-6114350-A | Cyanine dyes and synthesis methods thereof | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-09-05 | — | — | US | disclosed |