SCHEMBL3971392

SCHEMBL3971392

Cc1ccc(SNc2ccc(Nc3ccccc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.67
L3MBTL1 Q9Y468 5/20 0.48
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
ALOX12 P18054 3/20 0.48
ALOX15 P16050 2/20 0.48
TSHR P16473 2/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
MAPK1 P28482 1/20 0.48
PTGS2 P35354 1/20 0.48
HTR2B P41595 1/20 0.48
GAA P10253 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
NPSR1 Q6W5P4 1/20 0.46
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
KDM1A O60341 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11289053 0.92 HPGD (0.52) HPGDL3MBTL1ALDH1A1TDP1ALOX12
SCHEMBL19234396 0.88 HPGD (0.52) HPGDALDH1A1HSD17B10TDP1ALOX12
SCHEMBL9461706 0.82 HPGD (1.00) HPGDL3MBTL1ALDH1A1HSD17B10TDP1
SCHEMBL172875 0.82 HPGD (1.00) HPGDL3MBTL1ALDH1A1HSD17B10TDP1
SCHEMBL24137168 0.82 HPGD (1.00) HPGDL3MBTL1ALDH1A1HSD17B10TDP1
Diphenylamine SCHEMBL9215415 0.79 HPGD (0.94) HPGDL3MBTL1ALDH1A1HSD17B10TDP1
SCHEMBL24383303 0.79 HPGD (0.68) HPGDL3MBTL1ALDH1A1HSD17B10TDP1
SCHEMBL311562 0.77 HSD17B10 (0.50) HPGDL3MBTL1ALDH1A1HSD17B10TDP1
SCHEMBL24897900 0.77 MAPT (0.37) HPGDALDH1A1TDP1ALOX12MEN1
SCHEMBL19932343 0.77 MAPT (0.37) HPGDALDH1A1TDP1ALOX12MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1201414-B1 Method of manufacturing the sidewall of a pneumatic tire SUMITOMO RUBBER IND (JP) 2009-05-06 EP disclosed
US-7513281-B2 Method of manufacturing pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2009-04-07 US disclosed
US-7060146-B2 Method of manufacturing pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2006-06-13 US disclosed
US-20050145314-A1 Method of manufacturing pneumatic tire SUMITOMO RUBBER INDUSTRIES, INC. (JP) 2005-07-07 US disclosed
US-20020074077-A1 Method of manufacturing pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2002-06-20 US disclosed
EP-1201414-A2 Method of manufacturing the sidewall of a pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2002-05-02 EP disclosed