SCHEMBL3971457

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3975542	0.89	MAP2K1 (0.49)	CSF1RMAP2K1MAP2K2KDM4EMEN1
	SCHEMBL3980786	0.89	MAP2K1 (0.47)	MAP2K1MAP2K2
	SCHEMBL3969037	0.88	MAP2K1 (0.43)	MAP2K1MAP2K2SYKHDAC6
	SCHEMBL3974237	0.86	IRAK4 (0.37)	CSF1RMAP2K1MAP2K2CYP1A2CYP3A4
	SCHEMBL14500017	0.84	MAP2K1 (0.55)	CSF1RMAP2K1MAP2K2KCNH2SCN5A
	SCHEMBL14500013	0.83	MAP2K1 (0.56)	MAP2K1MAP2K2CYP2C9KCNH2
	SCHEMBL3978663	0.82	CSF1R (0.41)	CSF1RMAP2K1CYP1A2SYK
	SCHEMBL3973939	0.82	CSF1R (0.44)	CSF1RMAP2K1MAP2K2KCNH2SCN5A
	SCHEMBL13843594	0.81	CSF1R (0.43)	CSF1RMAP2K1MAP2K2SYKKCNH2
	SCHEMBL13842022	0.81	MAP2K1 (0.45)	CSF1RMAP2K1MAP2K2SYKSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.