Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146566 | 0.85 | POLA1 (0.43) | TP53MAPT | |
| SCHEMBL379238 | 0.74 | RAPGEF4 (0.63) | TP53MAPTHTT | |
| SCHEMBL5309531 | 0.74 | TP53 (0.63) | TP53MAPTHTT | |
| SCHEMBL17057465 | 0.73 | TP53 (1.00) | TP53MAPTHTT | |
| SCHEMBL5298937 | 0.72 | TP53 (0.71) | TP53MAPTHTT | |
| SCHEMBL21221811 | 0.72 | TP53 (0.61) | TP53MAPTHTT | |
| SCHEMBL4082607 | 0.72 | MAPT (0.68) | TP53MAPTHTT | |
| SCHEMBL21221777 | 0.72 | TP53 (0.56) | TP53MAPT | |
| SCHEMBL5299268 | 0.72 | TP53 (0.52) | TP53MAPTHTT | |
| SCHEMBL25912039 | 0.70 | RAPGEF4 (0.58) | TP53MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488577-B2 | non-radioactive assay in microtiter plate format enabling colorimetric or fluorimetric product detection for drug screening; solid phase synthesis | CAVIDI TECH AB (SE) | 2009-02-10 | — | — | US | disclosed |
| EP-1395675-B1 | A METHOD FOR MEASURING DNA POLYMERIZATION AND APPLICATIONS OF THE METHOD | CAVIDI TECH AB (SE) | 2006-01-18 | — | — | EP | disclosed |
| US-20040157230-A1 | Method for measuring dna polymerization and applications of the method | CAVIDI AB (SE) | 2004-08-12 | — | — | US | disclosed |
| EP-1395675-A1 | A METHOD FOR MEASURING DNA POLYMERIZATION AND APPLICATIONS OF THE METHOD | Cavidi Tech AB (SE) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002103039-A1 | A METHOD FOR MEASURING DNA POLYMERIZATION AND APPLICATIONS OF THE METHOD | CAVIDI TECH AB (SE) | 2002-12-27 | — | — | WO | disclosed |