Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 11/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31611813 | 0.85 | APP (0.44) | S1PR3S1PR1PSEN1PSEN2APH1B | |
| SCHEMBL3978580 | 0.85 | APP (0.44) | S1PR3S1PR1PSEN1PSEN2APH1B | |
| SCHEMBL6100359 | 0.85 | APP (0.44) | S1PR3S1PR1PSEN1PSEN2APH1B | |
| SCHEMBL29499491 | 0.85 | KCNQ3 (0.49) | CES2CES1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL991621 | 0.85 | KCNQ3 (0.49) | CES2CES1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL27753267 | 0.74 | APP (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14790427 | 0.74 | UGT2B7 (0.58) | — | |
| SCHEMBL27243952 | 0.73 | CES2 (0.49) | S1PR3S1PR1CES2CES1KCNQ3 | |
| SCHEMBL31240253 | 0.72 | APP (0.70) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1262317 | 0.72 | MAPT (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |