Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967995 | 0.90 | HSD11B1 (0.59) | HSD11B1CYP2D6AVPR1A | |
| SCHEMBL3972479 | 0.87 | HSD11B1 (0.56) | HSD11B1CYP2D6AVPR1A | |
| SCHEMBL4078055 | 0.82 | HSD11B1 (0.60) | HSD11B1CYP2D6 | |
| SCHEMBL350836 | 0.82 | HSD11B1 (0.60) | HSD11B1CYP2D6 | |
| SCHEMBL3971621 | 0.73 | HSD11B1 (0.69) | HSD11B1CYP2D6 | |
| SCHEMBL15515429 | 0.72 | AVPR1A (0.45) | HSD11B1AVPR1A | |
| SCHEMBL349521 | 0.72 | HSD11B1 (0.67) | HSD11B1CYP2D6AVPR1A | |
| SCHEMBL349309 | 0.71 | HSD11B1 (0.71) | HSD11B1CYP2D6 | |
| SCHEMBL350549 | 0.71 | HSD11B1 (0.60) | HSD11B1CYP2D6 | |
| SCHEMBL350477 | 0.71 | HSD11B1 (0.59) | HSD11B1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756063-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-03-25 | — | — | EP | claimed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | claimed |