⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165207 | 0.80 | — | — | |
| SCHEMBL15050449 | 0.78 | THRB (0.40) | — | |
| SCHEMBL271779 | 0.76 | THRB (0.38) | — | |
| SCHEMBL8698778 | 0.75 | MAPK1 (0.38) | — | |
| SCHEMBL8047034 | 0.74 | — | — | |
| SCHEMBL4967269 | 0.74 | — | — | |
| SCHEMBL23213971 | 0.73 | — | — | |
| SCHEMBL28863426 | 0.73 | TSHR (0.44) | — | |
| SCHEMBL23720675 | 0.73 | — | — | |
| SCHEMBL1227367 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257386-A1 | PYRROLO[1,2-b]PYRIDAZINE DERIVATIVES | GILEAD SCIENCES, INC. | 2023-08-17 | — | — | US | disclosed |
| US-11702414-B2 | Thiadiazole IRAK4 inhibitors | GILEAD SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20170114019-A1 | 18-20 MEMBER BI-POLYCYCLIC COMPOUNDS | HARO PHARMACEUTICAL INC. | 2017-04-27 | — | — | US | disclosed |
| US-8735048-B2 | Actinic ray-sensitive or radiation-sensitive resin composition, resist film using the composition and pattern forming method | FUJIFILM CORPORATION (JP) | 2014-05-27 | — | — | US | disclosed |
| US-20130071415-A1 | Heterocyclic Compounds as Janus Kinase Inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20120301817-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE COMPOSITION AND PATTERN FORMING METHOD | FUJIFILM CORPORATION (JP) | 2012-11-29 | — | — | US | disclosed |
| US-20120149691-A1 | Pyrrolo [1,2-b] Pyridazine Derivatives as Janus Kinase Inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| WO-2011093520-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE COMPOSITION AND PATTERN FORMING METHOD | FUJIFILM CORPORATION (JP) | 2011-08-04 | — | — | WO | disclosed |
| EP-1450811-B1 | Compounds specific to adenosine A1 and A3 receptors and uses thereof | OSI PHARM INC (US) | 2009-10-21 | — | — | EP | disclosed |
| WO-2009047577-A1 | PROCESS FOR PREPARATION OF ROSUVASTATIN ZINC SALT | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársaság (HU) | 2009-04-16 | — | — | WO | disclosed |
| EP-1221437-A1 | Process for the preparation of primary and secondary amines from nitriles | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-10 | — | — | EP | disclosed |
| US-6017907-A | Structural analogues of vitamin D | LABORATOIRE THERAMEX S.A. (MC) | 2000-01-25 | — | — | US | disclosed |
| EP-0972762-A2 | Novel structural analogues of vitamin D | LABORATOIRE THERAMEX (MC) | 2000-01-19 | — | — | EP | disclosed |
| WO-1999032429-A2 | METHOD FOR PRODUCING SECONDARY AMINES FROM NITRILES AND PRIMARY AMINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-01 | — | — | WO | disclosed |
| EP-0673918-B1 | Process for the preparation of peralkylated amines | BASF AG (DE) | 1999-06-02 | — | — | EP | disclosed |
| US-5894074-A | Preparation of tertiary amines from nitriles and secondary amines | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-13 | — | — | US | disclosed |
| EP-0869113-A2 | Process for the preparation of tertiary amines fromnitriles and secondary amines | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-07 | — | — | EP | disclosed |
| US-5463130-A | Preparation of peralkylated amines | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0673918-A1 | Process for the preparation of peralkylated amines | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |
| US-4372971-A | Heterocyclic prostaglandin type compounds, medicaments containing them and processes for the preparation and use of these heterocyclic compounds and medicaments | GRUENENTHAL GMBH (DE) | 1983-02-08 | — | — | US | disclosed |