Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 17/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 17/20 | 0.42 |
| ▸ | MCTS1 | Q9ULC4 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930245 | 0.96 | SLC16A3 (0.43) | SLC16A3SLC16A1MCTS1KMT2AALDH1A1 | |
| SCHEMBL1929476 | 0.96 | SLC16A3 (0.43) | SLC16A3SLC16A1MCTS1KMT2AALDH1A1 | |
| SCHEMBL1930244 | 0.96 | SLC16A3 (0.43) | SLC16A3SLC16A1MCTS1KMT2AALDH1A1 | |
| SCHEMBL4389989 | 0.92 | SLC16A3 (0.42) | SLC16A3SLC16A1MCTS1KMT2AALDH1A1 | |
| SCHEMBL4383910 | 0.92 | SLC16A3 (0.42) | SLC16A3SLC16A1MCTS1KMT2AALDH1A1 | |
| SCHEMBL6265093 | 0.91 | ALDH1A1 (0.44) | SLC16A3SLC16A1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4479975 | 0.88 | SLC16A3 (0.43) | SLC16A3SLC16A1MCTS1KMT2AALDH1A1 | |
| SCHEMBL3974627 | 0.88 | ALDH1A1 (0.47) | SLC16A3SLC16A1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3971072 | 0.88 | ALDH1A1 (0.47) | SLC16A3SLC16A1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4386165 | 0.88 | SLC16A3 (0.43) | SLC16A3SLC16A1MCTS1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778655-B1 | 2 - { - 3 2 - (PHENYL)-OXAZOL-4-YLMETHOXYL-CYCLOHEXYLMETHOXY}-PROPIONIC ACID DERIVATIVES USED AS PPAR LIGANDS (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS) FOR THE TREATMENT OF HYPERLIPIDAEMIE AND DIABETES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-05-06 | — | — | EP | disclosed |