Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472199 | 0.76 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL4472203 | 0.76 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL815315 | 0.76 | NFE2L2 (0.70) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL14491082 | 0.75 | MEN1 (0.69) | CYP1A2CYP3A4CYP2D6CYP2C9KDM4E | |
| SCHEMBL21951064 | 0.74 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL499293 | 0.72 | MAOB (0.59) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL499292 | 0.72 | MAOB (0.59) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL13359041 | 0.72 | MAPT (0.66) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL21219011 | 0.72 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL499507 | 0.72 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566737-B2 | Combinations of substituted 1,3-diphenylprop-2-en-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2009-07-28 | — | — | US | disclosed |
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | PSEN1, BACE1, PSEN2 | CYP1A2 1583/4885CYP3A4 3088/4885CYP2D6 2461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.