Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 6/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248730 | 0.88 | P2RX4 (0.35) | P2RX4P2RX1P2RX3P2RX7SMN1; SMN2 | |
| SCHEMBL3453648 | 0.78 | LMNA (0.36) | P2RX4P2RX1P2RX3P2RX7SMN1; SMN2 | |
| SCHEMBL329494 | 0.78 | LMNA (0.32) | P2RX4P2RX1P2RX3LMNATSHR | |
| SCHEMBL29486049 | 0.74 | MAPT (0.38) | P2RX4P2RX1P2RX3P2RX7SMN1; SMN2 | |
| SCHEMBL3714615 | 0.74 | MAPT (0.38) | P2RX4P2RX1P2RX3P2RX7SMN1; SMN2 | |
| Iodide SCHEMBL11405105 | 0.73 | MAPT (0.37) | P2RX4P2RX1P2RX3P2RX7SMN1; SMN2 | |
| SCHEMBL29434173 | 0.72 | P2RX4 (0.37) | P2RX4P2RX1P2RX3P2RX7SMN1; SMN2 | |
| SCHEMBL1198914 | 0.72 | P2RX4 (0.37) | P2RX4P2RX1P2RX3P2RX7SMN1; SMN2 | |
| SCHEMBL3262059 | 0.72 | MAOB (0.33) | P2RX4HRH1 | |
| SCHEMBL3628666 | 0.72 | MAOB (0.33) | P2RX4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638566-A4 | SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1638566-A2 | SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005003064-A2 | SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-13 | — | — | WO | disclosed |
| WO-2005003065-A2 | SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-13 | — | — | WO | disclosed |