Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973168 | 1.00 | NR4A1 (0.47) | NR4A1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL30931819 | 0.93 | NR4A1 (0.54) | NR4A1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL32490152 | 0.93 | NR4A1 (0.54) | NR4A1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL3682352 | 0.93 | NR4A1 (0.54) | NR4A1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL3682351 | 0.93 | NR4A1 (0.54) | NR4A1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL5589850 | 0.91 | NR4A1 (0.53) | NR4A1MAOAMAOBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5664626 | 0.91 | NR4A1 (0.53) | NR4A1MAOAMAOBKDM4EALDH1A1 | |
| Bromide SCHEMBL8057298 | 0.90 | NR4A1 (0.51) | NR4A1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL18086818 | 0.84 | NR4A1 (0.49) | NR4A1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL5588926 | 0.84 | NR4A1 (0.49) | NR4A1MAOAMAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051956-A2 | PYRAZOLE-SUBSTITUTED ISOXAZOLINE INSECTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-23 | — | — | WO | disclosed |