Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613032 | 0.83 | POLB (0.71) | POLBFKBP1AGLAKMT2AHSD17B10 | |
| SCHEMBL15139607 | 0.83 | POLB (0.71) | POLBFKBP1AGLAKMT2AHSD17B10 | |
| SCHEMBL1853129 | 0.83 | POLB (0.71) | POLBFKBP1AGLAKMT2AHSD17B10 | |
| SCHEMBL3369957 | 0.80 | POLB (0.67) | POLBFKBP1AGLAKMT2AHSD17B10 | |
| SCHEMBL8724983 | 0.80 | POLB (0.70) | POLBFKBP1AGLAKMT2AHSD17B10 | |
| SCHEMBL3439600 | 0.80 | POLB (0.66) | POLBFKBP1AGLAKMT2AHSD17B10 | |
| SCHEMBL27830860 | 0.80 | POLB (0.66) | POLBKMT2AHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL10048553 | 0.80 | POLB (0.66) | POLBFKBP1AGLAKMT2AALDH1A1 | |
| SCHEMBL31634184 | 0.77 | POLB (0.62) | POLBKMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL11231122 | 0.76 | POLB (1.00) | POLBFKBP1AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100540536-C | Phenylpyridylpiperazcompounds compounds, their preparation method and the pharmaceutical composition that comprises them | SERVIER LAB (FR) | 2009-09-16 | — | — | CN | disclosed |
| US-7494995-B2 | Phenylpyridylpiperazine compounds | LES LABORATOIRES SERVIER (FR) | 2009-02-24 | — | — | US | disclosed |
| CN-1896062-A | New phenylpyridylpiperazine compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-01-17 | — | — | CN | disclosed |
| US-20060258671-A1 | Phenylpyridylpiperazine compounds | LES LABORATORIES SERVIER (FR) | 2006-11-16 | — | — | US | disclosed |
| EP-1721896-A1 | Phenylpyridinylpiperazin derivatives, the process to make them and the compositions containing them | Les Laboratoires Servier (FR) | 2006-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258671-A1 | Phenylpyridylpiperazine compounds | HRH4, HRH3, HRH2 | POLB 4533/4885FKBP1A 2495/4885GLA 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.