Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.68 |
| ▸ | CA1 | P00915 | 8/20 | 0.68 |
| ▸ | CA2 | P00918 | 8/20 | 0.68 |
| ▸ | CA7 | P43166 | 8/20 | 0.68 |
| ▸ | CA9 | Q16790 | 8/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344827 | 0.98 | CA12 (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5267852 | 0.86 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| Methyl 2,5-Dihydroxybenzoate SCHEMBL29457577 | 0.81 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Methyl 2,5-Dihydroxybenzoate SCHEMBL38890 | 0.81 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10819681 | 0.81 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13286843 | 0.79 | CA12 (0.73) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28895697 | 0.79 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10787290 | 0.78 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7089488 | 0.78 | CA12 (0.71) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8021559 | 0.78 | CA12 (0.61) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120087904-A1 | Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Skin Cancer | AmDerma Pharmaceuticals, LLC (US) | 2012-04-12 | — | — | US | disclosed |
| US-8101660-B2 | Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of skin cancer | AmDerma Pharmaceuticals, LLC (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110237555-A1 | USE OF 2,5-DIHYDROXYBENZENE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT OF ROSACEA | ACTION MEDICINES (ES) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120087904-A1 | Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Skin Cancer | CYP8B1, CYP26B1, CYP24A1 | CA12 431/4885CA1 1782/4885CA2 463/4885 |
| US-20110237555-A1 | USE OF 2,5-DIHYDROXYBENZENE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT OF ROSACEA | CYP8B1, CYP1B1, CYP26B1 | CA12 1207/4885CA1 2993/4885CA2 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.