Methyl 2,5-Dihydroxybenzoate

Methyl 2,5-Dihydroxybenzoate

SCHEMBL38890

COC(=O)c1cc(O)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 1.00
CA1 P00915 7/20 1.00
CA2 P00918 7/20 1.00
CA7 P43166 7/20 1.00
CA9 Q16790 7/20 1.00
CA14 Q9ULX7 7/20 1.00
PDK2 Q15119 1/20 0.71
PDK4 Q16654 1/20 0.71
EGFR P00533 5/20 0.62
PTGS2 P35354 2/20 0.62
LMNA P02545 1/20 0.59
TSHR P16473 1/20 0.59
ALOX5 P09917 1/20 0.57
XDH P47989 1/20 0.52
GAA P10253 1/20 0.52
NOX4 Q9NPH5 1/20 0.50
ALDH1A1 P00352 1/20 0.49
TP53 P04637 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl 2,5-Dihydroxybenzoate SCHEMBL29457577 1.00 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL158999 0.85 CA12 (0.74) CA12CA1CA2CA7CA9
Methyl 2-Hydroxy-5-Methoxybenzoate SCHEMBL29709382 0.84 CA1 (0.72) CA12CA1CA2CA7CA9
Methyl 2-Hydroxy-5-Methoxybenzoate SCHEMBL643758 0.84 CA1 (0.72) CA12CA1CA2CA7CA9
Methyl 2,4-Dihydroxybenzoate SCHEMBL30917273 0.83 CA12 (1.00) CA12CA1CA2CA7CA9
Methyl 2,4-Dihydroxybenzoate SCHEMBL382883 0.83 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL344827 0.83 CA12 (0.70) CA12CA1CA2CA7CA9
SCHEMBL122473 0.82 CA12 (0.69) CA12CA1CA2CA7CA9
SCHEMBL12874079 0.82 CA12 (0.69) CA12CA1CA2CA7CA9
SCHEMBL29640522 0.82 CA12 (0.69) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 936 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024126715-A1 METHOD USING LIGHT AND A COSMETIC COMPOSITION L'OREAL (FR) 2024-06-20 WO claimed
CN-117100662-A Whitening and freckle-removing composition, and preparation method and application thereof 广州善草纪化妆品有限公司 2023-11-24 CN claimed
US-11673997-B2 Work time to walk-on time ratio by adding a phenolic catalyst to polyaspartic flooring formulations COVESTRO LLC (US) 2023-06-13 US claimed
CN-113999386-B Polyaryletherketone resin containing carboxyl side group and synthesis method thereof 浙江鹏孚隆新材料有限公司 2023-06-06 CN claimed
US-20220313578-A1 METHODS AND COMPOSITIONS FOR IMPROVING SKIN L'OREAL (FR) 2022-10-06 US claimed
US-20220298101-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE WELLA GERMANY GMBH (DE) 2022-09-22 US claimed
CN-112573999-B Preparation method of 3-chlorogentitol 中国海洋大学 2022-09-02 CN claimed
CN-114805811-A Polyarylether resin containing carboxyl side group, synthesis method and application of polyarylether resin in coating 浙江鹏孚隆新材料有限公司 2022-07-29 CN claimed
US-11352705-B2 Hydrocarbon oxidation by water oxidation electrocatalysts in non-aqueous solvents CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-06-07 US claimed
EP-4004076-A1 IMPROVED WORK TIME TO WALK-ON TIME RATIO BY ADDING A PHENOLIC CATALYST TO POLYASPARTIC FLOORING FORMULATIONS Covestro LLC (US) 2022-06-01 EP claimed
EP-1219667-B1 Novel thioether derivatives, their method for production and use COMM RES LAB INDEPENDENT ADMIN (JP) 2004-08-04 EP claimed
US-6752934-B2 USED IN PACKAGING OR IN STORAGE IN CLOSED SPACES FOR PROTECTION OF THE CONVENTIONAL METALS FOR USE SUCH AS IRON, CHROMIUM, NICKEL, TIN, ZINC, ALUMINUM, COPPER AND THEIR ALLOYS AGAINST ATMOSPHERIC CORROSION EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2004-06-22 US claimed
US-6630578-B2 Which respond immediately by emission of light when stimulated with light or electric energy, and are useful as switching material of memory COMMUNICATIONS RESEARCH LABORATORY, INDEPENDENT ADMINISTRATIVE INSTITUTION (JP) 2003-10-07 US claimed
WO-2003075882-A2 METHOD OF DEPIGMENTING SKIN AND HAIRS GHISALBERTI CARLO (BR) 2003-09-18 WO claimed
US-20030171507-A1 Novel thioether derivatives, their method for production and use NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) 2003-09-11 US claimed
US-20030031583-A1 Vapor-phase corrosion inhibitors and method of preparing same EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2003-02-13 US claimed
EP-1219667-A2 Novel thioether derivatives, their method for production and use Communications Research Laboratory, Independent Administrative Institution (JP) 2002-07-03 EP claimed
US-20020072583-A1 Novel thioether derivatives, their method for production and use NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, INCORPORATED ADMINISTRATIVE AGENCY (JP) 2002-06-13 US claimed
US-6306203-B1 FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-10-23 US claimed
US-5908723-A Recording sheets XEROX CORPORATION (US) 1999-06-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220298101-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE PNMT, TYR, DDT CA12 4014/4885CA1 4858/4885CA2 4270/4885
US-20220313578-A1 METHODS AND COMPOSITIONS FOR IMPROVING SKIN TYR, CUTA, PAH CA12 3689/4885CA1 4793/4885CA2 3218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.