⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29269025 | 0.91 | ALDH1A1 (0.32) | — | |
| SCHEMBL608811 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL2406857 | 0.76 | — | — | |
| SCHEMBL11596506 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL3634614 | 0.69 | — | — | |
| SCHEMBL3369217 | 0.69 | — | — | |
| SCHEMBL11245909 | 0.69 | — | — | |
| SCHEMBL1765501 | 0.69 | — | — | |
| SCHEMBL11808418 | 0.69 | — | — | |
| SCHEMBL11598592 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527346-A | Fluorescent probe based on specific response of BODIPY dye to hypochlorous acid, preparation and application | 河南大学 | 2021-10-22 | — | — | CN | disclosed |
| EP-1554240-B1 | SUBSTITUTED TETRALINS AND INDANES AND THEIR USE | JANSSEN PHARMACEUTICA NV (BE) | 2009-05-06 | — | — | EP | disclosed |
| US-7351857-B2 | Methods of using substituted tetralins and indanes | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-01 | — | — | US | disclosed |
| CN-100354259-C | Substituted tetralins and indanes and their use | JANSSEN PHARMACEUTICA NV (BE) | 2007-12-12 | — | — | CN | disclosed |
| CN-100349864-C | Treating syndrome X with substituted tetralins and indanes | JANSSEN PHARMACEUTICA NV (BE) | 2007-11-21 | — | — | CN | disclosed |
| EP-1282610-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THE USE THEREOF IN MEDICAMENTS | BAYER SCHERING PHARMA AG (DE) | 2007-07-25 | — | — | EP | disclosed |
| US-20060247314-A1 | Substituted tetralins and indanes | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-11-02 | — | — | US | disclosed |
| CN-1798732-A | Substituted tetralins and indanes | JANSSEN PHARMACEUTICA NV (BE) | 2006-07-05 | — | — | CN | disclosed |
| US-20060094786-A1 | Treating syndrome X with substituted tetralins and indanes | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-04 | — | — | US | disclosed |
| US-20060074130-A1 | Methods of using substituted tetralins and indanes | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-04-06 | — | — | US | disclosed |
| EP-1206458-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THE USE THEREOF IN MEDICAMENTS | Schering Aktiengesellschaft (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001081324-A1 | BENZOXAZINE DERIVATIVES AND BENZOTHIAZINE DERIVATIVES HAVING NOS-INHIBITORY AND ANTIOXIDANT PROPERTIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-11-01 | — | — | WO | disclosed |
| WO-2001081323-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THE USE THEREOF IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-11-01 | — | — | WO | disclosed |
| CN-1319097-A | Benzoxazine and benzothiazine derivatives and their use in medicines | SCHERING AG (DE) | 2001-10-24 | — | — | CN | disclosed |
| EP-1114037-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN MEDICINES | Schering Aktiengesellschaft (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2001014347-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THE USE THEREOF IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-01 | — | — | WO | disclosed |
| CN-1278802-A | Benzoxazine and Benzothiazine derivatives and their use in pharmaceuticals | SCHERING AG (DE) | 2001-01-03 | — | — | CN | disclosed |
| EP-1015437-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-2000017173-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN MEDICINES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999012915-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |