⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23547600 | 0.75 | — | — | |
| SCHEMBL28637758 | 0.70 | GAA (0.45) | — | |
| SCHEMBL18670576 | 0.70 | — | — | |
| SCHEMBL8839155 | 0.69 | — | — | |
| SCHEMBL18670609 | 0.69 | CA12 (0.60) | — | |
| SCHEMBL20492242 | 0.65 | GAA (0.35) | — | |
| SCHEMBL23592712 | 0.63 | SMN1; SMN2 (0.58) | — | |
| SCHEMBL28233992 | 0.60 | SMN1; SMN2 (0.67) | — | |
| SCHEMBL1486989 | 0.60 | — | — | |
| SCHEMBL2723676 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118110-B1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-07-25 | — | — | EP | disclosed |
| EP-2118110-A1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | Bristol-Myers Squibb Company (US) | 2009-11-18 | — | — | EP | disclosed |
| US-7538102-B2 | Compounds for the treatment of Hepatitis C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-05-26 | — | — | US | disclosed |
| US-20080226592-A1 | Compounds for the Treatment of Hepatitis C | BRISTOL-MYERS SQUIBB COMPANY | 2008-09-18 | — | — | US | disclosed |
| WO-2008112851-A1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-18 | — | — | WO | disclosed |