⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973886 | 0.69 | — | — | |
| SCHEMBL28893781 | 0.67 | — | — | |
| SCHEMBL11688163 | 0.60 | CA1 (0.69) | — | |
| SCHEMBL4141702 | 0.60 | — | — | |
| SCHEMBL2723676 | 0.55 | — | — | |
| SCHEMBL391423 | 0.55 | — | — | |
| SCHEMBL2017488 | 0.53 | CA1 (1.00) | — | |
| SCHEMBL21356989 | 0.53 | CA1 (1.00) | — | |
| Sulfamide SCHEMBL5880 | 0.53 | — | — | |
| Sulfamate SCHEMBL1501118 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639882-A | CHEMICAL INTERMEDIATES FOR FORMING VIRICIDES INHIBITING LENTIVIRUSES | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | disclosed |
| US-5637707-A | STEREOSELECTIVELY ADDING ORGANONETALLIC REAGENT BY NUCLEOPHILIC ADDITION TO KETONE COMPOUND | G. D. SEARLE & CO. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0566556-B1 | 2-Substituted tertiary carbinol derivatives of 1,5-iminosugars as antiviral compounds | SEARLE & CO (US) | 1996-07-03 | — | — | EP | disclosed |
| US-5530132-A | VIRICIDES, HIV VIRUS | G. D. SEARLE & CO. (US) | 1996-06-25 | — | — | US | disclosed |
| US-5523406-A | STEREOSPECIFIC ALKYLATION BY NUCLEOPHILIC ADDITION AT C-2 WITH A GRIGNARD REAGENT | G. D. SEARLE & CO. (US) | 1996-06-04 | — | — | US | disclosed |
| US-5502193-A | VIRICIDES FOR AIDS | G. D. SEARLE & CO. (US) | 1996-03-26 | — | — | US | disclosed |
| US-5350854-A | AIDS treatment | G. D. SEARLE & CO. (US) | 1994-09-27 | — | — | US | disclosed |
| US-5258518-A | Antiviral agents, anti-HIV activity | G. D. SEARLE & CO. (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0566556-A1 | 2-Substituted tertiary carbinol derivatives of 1,5-iminosugars as antiviral compounds | G.D. Searle & Co. (US) | 1993-10-20 | — | — | EP | disclosed |